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Five Star Chemicals product Star San is a popular acid anionic sanitizer sold to homebrewers because of its relative safety and ease of use. Claims that acid anionic sanitizers are not effective at killing yeast have been made on various internet forums <ref>[https://www.homebrewersassociation.org/forum/index.php?topic=24447.msg312961#msg312961 User 'S. cerevisiae'. American Homebrewers Association forums. 10/05/2015. Retrieved 04/11/2018.]</ref><ref>[https://www.homebrewersassociation.org/forum/index.php?topic=4576.msg52894#msg52894 User 'richardt'. American Homebrewers Association forums. 11/15/2010. Retrieved 04/11/2018.]</ref>. These claims are based on the food science textbooks, "Principles of Food Sanitation," by Norman G. Marriott and Robert B. Gravani (2006) and "Basic Food Microbiology" by George Banward (1989), which contain conflicting information about the effectiveness of acid anionic sanitizers, and neither source contains experimental data nor references to experimental data. Furthermore, the provided explanation, which is that acid anionic sanitizers supposedly don't work effectively against yeast and molds is because acid anionic sanitizers are negatively charged and yeast are also negatively charged yet bacteria is killed because it is positively charged, is biologically incorrect according . According to [https://www.youtube.com/watch?v=0JC9n50RdVo Dr. Bryan Heit of Sui Generis blog] , both yeast and bacteria have negatively charged cell walls, and this fact has been well established in microbiology since the 1940's (Dr. Heit has published several [https://scholar.google.com/citations?user=8yxqYNgAAAAJ&hl=en&oi=ao peer-reviewed scientific studies on cell wall polarity]). While we are not aware of any publicly available published studies on the efficacy of StarSan, several studies with acid anionic sanitizers have confirmed that they are effective against non-spore forming yeast. [https://onlinelibrary.wiley.com/doi/full/10.1111/j.1750-3841.2007.00496.x Lee et al (2007)] found that an acid sanitizer very similar to Star San that uses citric acid instead of phosphate but the same surfactant (sodium dodecylbenzene sulfonate) took 5 minutes to kill ''Saccharomyces cerevisiae'', ''E. coli'', and ''Listeria innocua'' at room temperature (the ''E. coli'' was actually more resistant than the yeast), and one minute if the sanitizer was heated to 40°C on both metal and LDPE plastic (they compared the acid anionic sanitizer to 35% hydrogen peroxide, which killed all organisms with 15 seconds, indicating that this acid anionic sanitizer is effective at killing yeast, but it takes longer than a stronger chemical such as hydrogen peroxide). Five star [http://www.fivestarchemicals.com/wp-content/uploads/Star-San-HB4.pdf also recommends 5 minutes of contact time with Star san].  See [https://www.facebook.com/groups/MilkTheFunk/permalink/1436419659719577/ this MTF thread] for a more extensive explanation of why skepticism should be applied to the claim that acid anionic sanitizers are not effective at killing yeast.