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===Unmalted Barley===
Unmalted barley can contain higher levels of manganese ions, which can lead to oxidation as the resulting beer ages. Not all unmalted grain has higher levels of manganese ions; one study found that unmalted spelt does not contain elevated levels of this metal ion <ref>[https://www.sciencedirect.com/science/article/pii/S0023643820313372 Ionic composition of beer worts produced with selected unmalted grains. Monika Sterczyńska, Marta Stachnik, Aleksander Poreda, Katarzyna Pużyńska, Joanna Piepiórka-Stepuk, Grzegorz Fiutak, Marek Jakubowski. 2020. DOI: https://doi.org/10.1016/j.lwt.2020.110348.]</ref>.
===Smoked Grains===
Smoked grains may contain small levels of nitrosamines, a known carcinogen <ref>[https://www.sciencedirect.com/science/article/abs/pii/0278691595001166 N-nitrosodimethylamine in Spanish beers. M. Izquierdo-Pulido, J.F. Barbour, R.A. Scanlan. 1994.]</ref><ref>[https://en.wikipedia.org/wiki/Nitrosamine Nitrosamines. Wikipedia. Retrieved 11/15/2020.]</ref>.
==Enzymes, Extract Potential, and Nutrients==