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[https://en.wikipedia.org/wiki/Ethylenediaminetetraacetic_acid EDTA (ethylene diaminetetra-acetic acid)], chlorinated disinfectants, and hydrogen peroxide-based disinfectants such as Pur-Ox from Birko or Lerasept-O from Loeffler are effective at breaking up biofilms <ref name="Wirtanen_2001" /><ref>Brandon Jones. Private correspondence with Dan Pixley. 04/02/2018.</ref><ref>[https://www.reddit.com/r/TheBrewery/comments/6hqnvf/mtkettle_cleaning/dj0zd0s/ Levader on Reddit.com. "The Brewery". Retrieved 04/02/2018.]</ref>. Peracetic acid (PAA) has been shown to be effective against biofilmsin high concentrations <ref>[https://www.researchgate.net/publication/273439407_Disinfectant_testing_against_brewery-related_biofilms Disinfectant testing against brewery-related biofilms. Storgårds, Erna & Närhi, Mikko & Wirtanen, Gun. 2001.]</ref>, but its effectiveness decreases below 20°C. Chlorine and iodine-based disinfectants destroy microbe at colder temperatures, however, they are less effective in the presence of wort or other residues. Hot water is one of the most effective disinfectants, however, dry heat is not effective at killing bacteria (one strain of ''L. brevis'' was able to withstand 80°C dry heat for 60 minutes) <ref name="Wirtanen_2001" />.